Research

Finding the best ways to prevent and treat psychological health problems in military service members, veterans, and first responders

A Randomized Clinical Trial of Quetiapine Monotherapy vs. Treatment as Usual Polypharmacy for Postconcussive Syndrome in Veterans

PIMuhammad Rais Baig, MD
Location(s)San Antonio, Texas, and Albuquerque, New Mexico
Aim

Evaluate the effectiveness of quetiapine as a single medication therapy for postconcussive syndrome compared to treatment as usual with multiple medications following a mild traumatic brain injury (mTBI). Determine whether quetiapine effectively reduces postconcussive symptoms and functional disability and improves quality of life. Explore whether it enhances recovery by reducing medication side effects and increasing engagement in rehabilitation services.

StatusExpected to begin recruitment in summer of 2024

Combining Stellate Ganglion Block with Prolonged Exposure for PTSD: A Randomized Clinical Trial

PIAlan L. Peterson, PhD, ABPP (Lt Col, US Air Force, Ret.)
Location(s)San Antonio, TX, and Killeen, TX
Aim

Evaluate the efficacy of a stellate ganglion block (SGB) injection combined with massed Prolonged Exposure therapy (massed PE) for the treatment of PTSD in active duty military personnel.

StatusStudy currently open for recruitment in San Antonio

Randomized Controlled Trial of Intensive Multi-Couple Group Therapy for PTSD Versus Relationship Education in Military Couples

PISteffany Fredman, PhD
Location(s)Recruitment in South & Central Texas for retreats in San Antonio
Aim

Test an abbreviated, intensive, multi-couple group version of Cognitive-Behavioral Conjoint Therapy for PTSD in comparison to an established couples’ relationship education program. Evaluate how effectively the interventions reduce service members’ and veterans’ PTSD and related symptoms and simultaneously reduce their partners’ psychological distress and improve couples’ relationship satisfaction.

StatusCurrently recruiting participants for upcoming retreats

Accelerated Treatment for Co-occurring Insomnia, Nightmares, and PTSD

PICarmen McLean, PhD
Location(s)San Antonio, TX
Aim

Conduct a pilot study to develop an optimal treatment schedule, followed by a randomized clinical trial to determine the efficacy of cognitive-behavioral treatment for insomnia and nightmares in reducing sleep problems when integrated with PTSD treatment and delivered in an accelerated treatment format. Also explore the impact of the added sleep treatment on PTSD symptoms.

StatusRecruitment for pilot phase expected to begin in Fall 2023

An Effectiveness-Implementation Trial of Functional Restoration for Chronic Pain Management in Active Duty Military Personnel

PIAlan L. Peterson, PhD, ABPP (Lt Col, US Air Force, Ret.) & Katherine Comtois, PhD
Location(s)Six U.S. Department of Defense Military Health System sites nationwide
Aim

Evaluate the implementation and effectiveness of an evidence-based intervention for the nonpharmacological management of chronic pain in active duty military personnel.

StatusExpect to begin enrolling participants in Fall 2023

Project MARCH: Multisite Advancement of Research on Chronic Posttraumatic Headache

PIDonald McGeary, PhD
Location(s)Seven military installations nationwide
Aim

Compare the effectiveness of two forms of a manualized behavioral health intervention for posttraumatic headache (PTH) to usual care in a sample of U.S. military personnel and veterans with chronic PTH.

StatusCurrently enrolling research participants

Pilot Study of Brain Stimulation Combined with Writing Therapy for PTSD

PICasey Straud, PsyD
Location(s)San Antonio, TX
Aim

Evaluate the safety, feasibility, and psychological and physiological treatment benefits of transcranial direct current stimulation (tDCS), a noninvasive brain stimulation technique, when delivered in combination with Written Exposure Therapy for posttraumatic stress disorder.

StatusRecruitment closed; researchers analyzing data and publishing study findings

Assessment and Treatment of Chronic Anger and Aggression Following Military-Related Interpersonal and Institutional Betrayal: A Pilot Investigation

PIVanessa Jacoby, PhD, & Alan L. Peterson, PhD, ABPP (Lt Col, US Air Force, Ret.)
Location(s)Killeen, TX
Aim

Test the acceptability and feasibility of Countering Chronic Anger and Aggression Related to Trauma and Transgressions (CCAARTT), an intervention designed to help service members and veterans heal after military-related betrayal, and prevent interpersonal violence in the military community. Test whether CCAARTT reduces problematic anger and aggression in military personnel with a history of military-related betrayal, improves interpersonal functioning, and reduces symptoms of PTSD, depression, anxiety, or suicidal ideation.

StatusRecruitment of participants is expected to begin September 2023.

Written Exposure Therapy for Suicide Prevention: A Randomized Clinical Trial

PIBrian P. Marx, PhD
Location(s)Killeen, TX
Aim

Evaluate the efficacy of Written Exposure Therapy for Suicide Prevention compared with treatment as usual in reducing severity and incidence of self-injurious thoughts and behaviors among hospitalized active duty military personnel at risk for suicide. Evaluate a method of predicting who will benefit from the therapy.

StatusStudy expected to begin Spring 2023

REACT: Resilience Enhancement through Acceptance and Commitment Training

PIAlan L. Peterson, PhD, ABPP (Lt Col, US Air Force, Ret.)
Location(s)Killeen, TX
Aim

Develop and test a brief psychological intervention to enhance resilience and optimize readiness in U.S. military personnel.

StatusCurrently recruiting study participants
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