Pilot Study of Brain Stimulation Combined with Writing Therapy for PTSD
| PI | Casey Straud, PsyD |
| Location(s) | San Antonio, TX |
| Aim | Evaluate the safety, feasibility, and psychological and physiological treatment benefits of transcranial direct current stimulation (tDCS), a noninvasive brain stimulation technique, when delivered in combination with Written Exposure Therapy for posttraumatic stress disorder. |
| Status | Recruitment closed; researchers analyzing data and publishing study findings |
Assessment and Treatment of Chronic Anger and Aggression Following Military-Related Interpersonal and Institutional Betrayal: A Pilot Investigation
| PI | Vanessa Jacoby, PhD, & Alan L. Peterson, PhD, ABPP (Lt Col, US Air Force, Ret.) |
| Location(s) | Killeen, TX |
| Aim | Test the acceptability and feasibility of Countering Chronic Anger and Aggression Related to Trauma and Transgressions (CART), an intervention designed to help service members and veterans heal after military-related betrayal, and prevent interpersonal violence in the military community. Test whether CART reduces problematic anger and aggression in military personnel with a history of military-related betrayal, improves interpersonal functioning, and reduces symptoms of PTSD, depression, anxiety, or suicidal ideation. |
| Status | Currently recruiting research participants |
Written Exposure Therapy for Suicide Prevention: A Randomized Clinical Trial
| PI | Brian P. Marx, PhD |
| Location(s) | Killeen, TX |
| Aim | Evaluate the efficacy of Written Exposure Therapy for Suicide Prevention compared with treatment as usual in reducing severity and incidence of self-injurious thoughts and behaviors among hospitalized active duty military personnel at risk for suicide. Evaluate a method of predicting who will benefit from the therapy. |
| Status | Study expected to begin in Fall 2024 |
Enhancing Resiliency and Optimizing Readiness in Military Personnel
| PI | Alan L. Peterson, PhD, ABPP (Lt Col, US Air Force, Ret.) |
| Location(s) | Killeen, TX |
| Aim | Develop and test a brief psychological intervention to enhance resilience and optimize readiness in U.S. military personnel. |
| Status | Currently recruiting study participants |
Decreasing Suicide Risk among Service Members with Posttraumatic Stress Using Written Exposure Therapy
| PI | Brian P. Marx, PhD |
| Location(s) | Killeen, TX |
| Aim | Determine whether Written Exposure Therapy for Suicide reduces suicidal thoughts and behaviors and posttraumatic stress symptoms (PTSS); determine whether reductions in PTSS severity lead to fewer suicidal thoughts and behaviors. |
| Status | Enrollment complete |
Web-Based Provider Training for Cognitive Behavioral Therapy for Nightmares
| PI | Kristi Pruiksma, PhD |
| Location(s) | San Antonio, TX |
| Aim | Develop and evaluate an online training program for Cognitive Behavioral Therapy for Nightmares |
| Status | Program preparation and website development through summer 2022. Testing and evaluation to be conducted from fall 2022 through summer 2023, followed by formal launch of website. |
Two-Armed Pilot Randomized Controlled Trial of Massed Prolonged Exposure Plus Cannabidiol or Placebo for Posttraumatic Stress Disorder
| PI | Casey Straud, PsyD |
| Location(s) | San Antonio, TX |
| Aim | Examine the safety, feasibility, and symptom reductions associated with cannabidiol (CBD) in military veterans receiving 2 weeks of daily treatment with Prolonged Exposure, a leading therapy for posttraumatic stress disorder (PTSD). Evaluate potential biochemical and physiological changes associated with CBD vs. placebo and the relationship of those changes with the physiological stress response and PTSD symptom reduction. |
| Status | Enrollment complete. Analyzing data for publication of study findings. |
Targeting Chronic Pain in Military Primary Care Settings Using Internal Behavioral Health Consultants
| PI | Donald McGeary, PhD, & Jeffrey Goodie, PhD |
| Location(s) | Killeen, Texas; San Antonio, Texas; Las Vegas, Nevada |
| Aim | Enhance delivery of chronic pain care in U.S. military primary care clinics by developing a manual and training program for providers in a drug-free pain management therapy that helps to reduce the use of opioid medications; evaluate the program in a pragmatic clinical trial involving patients with chronic pain. |
| Status | Enrollment in Phase II began in 2021 and continues at San Antonio sites. Fort Hood and Nellis Air Force Base sites now closed to recruitment. |
Multi-Couple Group Intervention for PTSD
| PI | Steffany Fredman, PhD |
| Location(s) | Killeen, TX |
| Aim | Obtain preliminary data on the feasibility and efficacy of delivering couple-based treatment for PTSD within a multiple-couple group setting during a weekend retreat; evaluate the therapy’s impact on the severity of service members’ and veterans’ PTSD symptoms and co-occurring conditions, partners’ psychological well-being, and each partner’s relationship satisfaction. |
| Status | Enrollment closed. Investigators analyzing data and publishing study findings. |
A Pilot Randomized Controlled Trial of Treatment for Trauma-Related Nightmares in Active Duty Military Personnel
| PI | Kristi Pruiksma, PhD |
| Location(s) | Killeen, TX |
| Aim | Working with active duty military personnel who suffer from trauma-related nightmares, obtain preliminary data on the efficacy of a form of cognitive-behavioral therapy designed for treating nightmares. |
| Status | Enrollment closed. Investigators analyzing data and publishing study findings. |

